3. Faculty of Medicine: Poslední příspěvky
Zobrazují se záznamy 41-60 z 74
-
Severe COVID-19 associated hyperglycemia is caused by beta cell dysfunction: a prospective cohort study
původní článek
open access
vydavatelská verze
2023
,Nutrition & Diabetes
,13
(July)
BACKGROUND: COVID-19, an infectious disease caused by SARS-CoV-2, was shown to be associated with an increased risk of new-onset diabetes. Mechanisms contributing to the development of hyperglycemia are still unclear. We ...
-
A randomized comparison of His bundle pacing versus right ventricular pacing: Effect on left ventricular function and biomarkers of collagen metabolism
původní článek
open access
vydavatelská verze
2023
,Kardiologia Polska
,81
(5)
BACKGROUND: Right ventricular pacing (RVP) can result in pacing-induced cardiomyopathy (PICM). It is unknown whether specific biomarkers reflect differences between His bundle pacing (HBP) and RVP and predict a decrease ...
-
Nonprocedural bleeding after left atrial appendage closure versus direct oral anticoagulants: A subanalysis of the randomized PRAGUE-17 trial
původní článek
open access
vydavatelská verze
2023
,Journal of Cardiovascular Electrophysiology
,34
(9)
INTRODUCTION: Observational studies have shown low bleeding rates in patients with atrial fibrillation (AF) treated by left atrial appendage closure (LAAC); however, data from randomized studies are lacking. This study ...
-
Prevalence of iodine deficiency among vegan compared to vegetarian and omnivore children in the Czech Republic: cross-sectional study
původní článek
open access
vydavatelská verze
2023
,European Journal of Clinical Nutrition
,77
(11)
BACKGROUND: The intake and homeostasis of iodine, an essential micronutrient that plays a vital role in thyroid physiology, is of particular concern with the increasing popularity of vegetarian (VG) and vegan (VN) diets. ...
-
Acute ischaemic stroke: recent advances in reperfusion treatment
přehledový článek
open access
vydavatelská verze
2023
,European Heart Journal
,44
(14)
During the last 5-7 years, tremendous progress was achieved in the reperfusion treatment of acute ischaemic stroke during its first few hours from symptom onset. This review summarizes the latest evidence from randomized ...
-
Targets for pollutants in rat and human pancreatic beta-cells: The effect of prolonged exposure to sub-lethal concentrations of hexachlorocyclohexane isomers on the expression of function- and survival-related proteins
původní článek
open access
vydavatelská verze
2023
,Environmental Toxicology and Pharmacology
,104
(November)
Decades after most countries banned hexachlorocyclohexane, HCH isomers still pollute the environment. Many studies described HCH as a pro-diabetic factor; nevertheless, the effect of HCH isomers on pancreatic beta-cells ...
-
Muscle Lipid Oxidation Is Not Affected by Obstructive Sleep Apnea in Diabetes and Healthy Subjects
původní článek
open access
vydavatelská verze
2023
,International Journal of Molecular Sciences
,24
(6)
The molecular mechanisms linking obstructive sleep apnea (OSA) with type 2 diabetes mellitus (T2DM) remain unclear. This study investigated the effect of OSA on skeletal muscle lipid oxidation in nondiabetic controls and ...
-
Is it a true left bundle branch block or not?
letter to the editors
open access
vydavatelská verze
2023
,Journal of Interventional Cardiac Electrophysiology
,66
(6)
Among patients with wide QRS complexes of nonRBBB morphologies on ECG, there are those with preserved left septal Purkinje activation, i.e., intraventricular conduction delay (IVCD). Unfortunately, twelve lead ECGs do not ...
-
Left ventricular resynchronization with left bundle branch area pacing: does the type of capture matter?
editorial
open access
vydavatelská verze
2023
,Europace
,25
(6)
Cardiac resynchronization therapy (CRT) with biventricular pacing (BiV) has been a mainstream treatment in heart failure patients with wide QRS complexes for two decades. In recent years, left bundle branch pacing (LBBP) ...
-
Bipolar anodal septal pacing with direct LBB capture preserves physiological ventricular activation better than unipolar left bundle branch pacing
původní článek
open access
vydavatelská verze
2023
,Frontiers in Cardiovascular Medicine
,10
(March)
BACKGROUND: Left bundle branch pacing (LBBP) produces delayed, unphysiological activation of the right ventricle. Using ultra-high-frequency electrocardiography (UHF-ECG), we explored how bipolar anodal septal pacing with ...
-
Transseptal puncture in left atrial appendage closure guided by 3D printing and multiplanar CT reconstruction
původní článek
open access
vydavatelská verze
2023
,Catheterization and Cardiovascular Interventions
,102
(7)
BACKGROUND: The presented study investigates the application of bi-arterial 3D printed models to guide transseptal puncture (TSP) in left atrial appendage closure (LAAC). AIMS: The objectives are to (1) test the feasibility ...
-
Trends in outcomes of women with myocardial infarction undergoing primary angioplasty - Analysis of randomized trials
původní článek
open access
vydavatelská verze
2023
,Frontiers in Cardiovascular Medicine
,9
(January)
Background: Sex- and gender-associated differences determine the disease response to treatment.Aim: The study aimed to explore the hypothesis that progress in the management of STE-myocardial infarction (STEMI) overcomes ...
-
Serious Immune-related Adverse Events Are Associated With Greater Efficacy of Nivolumab Therapy Against Non-small Cell Lung Cancer
původní článek
open access
vydavatelská verze
2023
,In Vivo
,37
(5)
BACKGROUND/AIM: The aim of this study was to investigate possible association between adverse events of nivolumab therapy and the effectiveness of treatment in patients with non-small cell lung cancer (NSCLC). Focusing on ...
-
Human polyomaviruses in psoriasis patients on biologic treatment
abstrakt v elektronické podobě
open access
postprint
2023
,Neuveden
Biologic therapy poses a higher risk of viral infection for patients, however current knowledge of human polyomavirus infection in psoriasis patients is stilllimited. In this study, we evaluate the prevalence of BK ...
-
Integrative analysis of mRNA and miRNA expression profiles and somatic variants in oxysterol signaling in early-stage luminal breast cancer
původní článek
open access
postprint
2023
,Molecular Oncology
,17
(10)
Oxysterols, oxidized derivatives of cholesterol, act in breast cancer (BC) as selective estrogen receptor modulators and affect cholesterol homeostasis, drug transport, nuclear and cell receptors, and other signaling ...
-
Changes on chromosome 11p15.5 as specific marker for embryonal rhabdomyosarcoma?
původní článek
open access
postprint
2023
,Genes, Chromosomes & Cancer
,62
(12)
Rhabdomyosarcomas (RMS) constitute a heterogeneous spectrum of tumors with respect to clinical behavior and tumor morphology. The paternal uniparental disomy (pUPD) of 11p15.5 is a molecular change described mainly in ...
-
Sborník materiálů z replikace výzkumné studie RN4CAST: Modul Evidence Based Practice ve výuce ošetřovatelské péče
Proceedings of the Replication of the RN4CAST Research Study: Evidence Based Practice Module in Nursing Education
sborník
embargo
vydavatelská verze
2023
,Praha
,Univerzita Karlova, 3. lékařská fakulta, Ústav ošetřovatelství
Sborník představuje historii tvorby a realizace projektu Modul Evidence based practice ve výuce ošetřovatelské péče v letech 2017-2022. Sborník obsahuje čtyři hlavní okruhy, které byly v pilotním projektu ověřené prakticky ...
-
Epidemic spread of KPC-producing bacteria in the Czech Republic
abstrakt v konferenčním sborníku
embargo
vydavatelská verze
2022
,Czech Chemical Society Symposium Series
,20
(6)
Carbapenems are currently last-resort antibiotics for the therapy of infections caused by multidrug-resistant Gram-negative bacteria. Therefore, the resistence to those drugs represents a significant threat of current ...
-
MUC13-miRNA-4647 axis in colorectal cancer: Prospects to identifications of risk factors and clinical outcomes
původní článek
open access
vydavatelská verze
2023
,Oncology Letters
,25
(2)
MUC13, a transmembrane mucin glycoprotein, is overexpressed in colorectal cancer (CRC), however, its regulation and functions are not fully understood. It has been shown that MUC13 protects colonic epithelial cells from ...
-
Prevalence of myocardial injury in patients after acute ischaemic stroke according to standard criteria
původní článek
open access
vydavatelská verze
2023
,European Heart Journal: Supplements
,25
(Suppl. E)
This study examined the prevalence of acute and chronic myocardial injury according to standard criteria in patients after acute ischaemic stroke (AIS) and its relation to stroke severity and short-term prognosis. Between ...
