Repozitář publikační činnosti UK: Poslední příspěvky
Zobrazují se záznamy 561-580 z 938
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Survival in melanoma in the nordic countries into the era of targeted and immunological therapies
původní článek
embargo
vydavatelská verze
2023
,European Journal of Cancer
,186
(June)
Objectives: Survival in melanoma has been increasing and the most recent interest is to observe the population-level impact of novel targeted therapies and immunotherapy. We analysed survival in melanoma from Denmark (DK), ...
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The dynamics of telomere length in primary and metastatic colorectal cancer lesions
původní článek
embargo
vydavatelská verze
2023
,Scientific Reports
,13
(1)
Telomeric sequences, the structures comprised of hexanucleotide repeats and associated proteins, play a pivotal role in chromosome end protection and preservation of genomic stability. Herein we address telomere length ...
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Preferred β-lactone synthesis can explain high rate of false-negative results in the detection of OXA-48-like carbapenemases
abstrakt v konferenčním sborníku
embargo
vydavatelská verze
2022
,Czech Chemical Society Symposium Series
,20
(6)
The resistance to carbapenems is usually mediated by enzymes hydrolyzing β-lactam ring. Recently, an alternative way of the modification of the antibiotic, a β-lactone formation by OXA-48-like enzymes, in some carbapenems ...
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Epidemic spread of KPC-producing bacteria in the Czech Republic
abstrakt v konferenčním sborníku
embargo
vydavatelská verze
2022
,Czech Chemical Society Symposium Series
,20
(6)
Carbapenems are currently last-resort antibiotics for the therapy of infections caused by multidrug-resistant Gram-negative bacteria. Therefore, the resistence to those drugs represents a significant threat of current ...
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Experimental Treatment with Edaravone in a Mouse Model of Spinocerebellar Ataxia 1
původní článek
open access
vydavatelská verze
2023
,International Journal of Molecular Sciences
,24
(13)
Edaravone is a mitochondrially targeted drug with a suggested capability to modify the course of diverse neurological diseases. Nevertheless, edaravone has not been tested yet in the context of spinocerebellar ataxia 1 ...
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Theranostics Nanomedicine Applications for Colorectal Cancer and Metastasis: Recent Advances
původní článek
open access
vydavatelská verze
2023
,International Journal of Molecular Sciences
,24
(9)
Colorectal cancer (CRC) is the third most common cancer worldwide, and metastatic CRC is a fatal disease. The CRC-affected tissues show several molecular markers that could be used as a fresh strategy to create newer methods ...
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Personal comorbidities and their subsequent risks for liver, gallbladder and bile duct cancers
původní článek
open access
vydavatelská verze
2023
,International Journal of Cancer
,152
(6)
Many environmental risk factors for hepatobiliary cancers are known but whether they are associated with specific cancer types is unclear. We present here a novel approach of assessing standardized incidence ratios (SIRs) ...
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Long-term survival trends in solid cancers in the Nordic countries marking timing of improvements
původní článek
open access
vydavatelská verze
2023
,International Journal of Cancer
,152
(9)
Survival studies are an important indicator of the success of cancer control. We analyzed the 5-year relative survival in 23 solid cancers in Denmark, Finland, Norway and Sweden over a 50-year period (1970-2019) at the ...
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MUC13-miRNA-4647 axis in colorectal cancer: Prospects to identifications of risk factors and clinical outcomes
původní článek
open access
vydavatelská verze
2023
,Oncology Letters
,25
(2)
MUC13, a transmembrane mucin glycoprotein, is overexpressed in colorectal cancer (CRC), however, its regulation and functions are not fully understood. It has been shown that MUC13 protects colonic epithelial cells from ...
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Worldwide Media Visibility of NATO, the European Union, and the United Nations in Connection to the Russia-Ukraine War
původní článek
open access
vydavatelská verze
2023
,Czech Journal of International Relations : Mezinárodní vztahy
,58
(1)
This article presents a theoretical and descriptive account of the worldwide media visibility of NATO, the European Union, and the United Nations in connection to the Russia-Ukraine war. I formulate a theoretical framework ...
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European Arrest Warrant – Mutual Trust and Mistrust Among EU Member States
původní článek
open access
vydavatelská verze
2023
,The Lawyer Quarterly
,13
(2)
The Europeanisation process for criminal law still faces many challenges today. The first of them is the concept of state sovereignty in the matter of criminal jurisdiction. The European arrest warrant (EAW) exemplifies ...
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Regulatory Model of the Budgetary Discipline Enforcement
Model regulacyjny przestrzegania dyscypliny finansów publicznych
původní článek
open access
vydavatelská verze
2023
,Studia Iuridica Lublinensia
,32
(1)
The budgetary discipline is an important part of a proper public expenditure management. However, it is not a well-researched subject with a strong theoretical background, nor is it in many countries well-arranged and ...
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Role of TRAF6 adaptor in the immune responses to murine polyomavirus
abstrakt v konferenčním sborníku
open access
vydavatelská verze
2023
,Tübingen
,Novel Concepts in Innate immunity
Polyomaviruses are associated with many diseases due to their ability to persistently infect the host. Since 2008, twelve new human polyomaviruses have been discovered. Among the new species, Merkel cell polyomavirus (MCPyV) ...
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Evropská úmluva o lidských právech: praktický průvodce
příručka
embargo
vydavatelská verze
2022
,Praha
,Právnická fakulta Univerzity Karlovy
Všem zájemcům o lidská práva doporučujeme praktického průvodce Evropskou úmluvou o lidských právech od autorů, kteří se lidskými právy denně zabývají. Záměrem knihy je představit šíři otázek, kterými se úmluva zabývá, a ...
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Cytoplasmic Tail of MT1-MMP: A Hub of MT1-MMP Regulation and Function
přehledový článek
open access
vydavatelská verze
2023
,International Journal of Molecular Sciences
,24
(6)
MT1-MMP (MMP-14) is a multifunctional protease that regulates ECM degradation, activation of other proteases, and a variety of cellular processes, including migration and viability in physiological and pathological contexts. ...
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Revealing the Complex Relationship Among Hyperspectral Reflectance, Photosynthetic Pigments, and Growth in Norway Spruce Ecotypes
původní článek
open access
vydavatelská verze
2022
,Frontiers in Plant Science
,13
(May)
Norway spruce has a wide natural distribution range, harboring substantial physiological and genetic variation. There are three altitudinal ecotypes described in this species. Each ecotype has been shaped by natural selection ...
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Attention Bias and Recognition of Sexual Images
původní článek
embargo
vydavatelská verze
2020
,Frontiers in Psychology [online]
,11
(listopad 2020)
Attention to sexual stimuli is necessary for the development of sexual response, yet while there is some evidence of attention bias in favor of sexual stimuli, the direction and magnitude of the effect remain unknown. A ...
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Repertoire and efficiency of students' strategies for general-reference maps
původní článek
open access
vydavatelská verze
2022
,ISPRS International Journal of Geo-Information
,11
(2)
Maps are not just powerful tools to communicate spatial information; they also have significant educational potential to develop students' knowledge, skills, and thinking. To fully exploit this potential, deep research is ...
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Agroforestry in the Czech Republic: What hampers the comeback of a once traditional land use system?
původní článek
open access
vydavatelská verze
2022
,Agronomy
,12
(1)
The interest in re-implementing agroforestry (AF) in European agriculture due to its environmental benefits has been growing exponentially. We reviewed the historical background and the current state (extent, farmers' ...
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Metabolism of Aldoximes and Nitriles in Plant-Associated Bacteria and Its Potential in Plant-Bacteria Interactions
přehledový článek
open access
vydavatelská verze
2022
,Microorganisms
,10
(3)
In plants, aldoximes per se act as defense compounds and are precursors of complex defense compounds such as cyanogenic glucosides and glucosinolates. Bacteria rarely produce aldoximes, but some are able to transform them ...
