Now showing items 481-500 of 1882

    • Disease-modifying treatment and disability progression in subclasses of patients with primary progressive MS: results from the Big MS Data Network 

      original article

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      Lorscheider, Johannes

      ;

      Signori, Alessio

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      Subramaniam, Suvitha

      ;

      Benkert, Pascal

      ;

      Vukusic, Sandra

      ;

      Trojano, Maria

      ;

      Hillert, Jan

      ;

      Glaser, Anna

      ;

      Hyde, Robert

      ;

      Spelman, Tim

      ;

      Magyari, Melinda

      ;

      Elberling, Frederik

      ;

      Pontieri, Luigi

      ;

      Koch-Henriksen, Nils

      ;

      Sorensen, Per Soelberg

      ;

      Gerlach, Oliver

      ;

      Prat, Alexandre

      ;

      Girard, Marc

      ;

      Eichau, Sara

      ;

      Grammond, Pierre

      ;

      Horáková, Dana

      ;

      Ramo-Tello, Cristina

      ;

      Roos, Izanne

      ;

      Buzzard, Katherine

      ;

      Scott, Jeanette Lechner

      ;

      Sanchez-Menoyo, Jose Luis

      ;

      Alroughani, Raed

      ;

      Prevost, Julie

      ;

      Kuhle, Jens

      ;

      Gray, Orla

      ;

      Mathey, Guillaume

      ;

      Michel, Laure

      ;

      Ciron, Jonathan

      ;

      De Seze, Jerome

      ;

      Maillart, Elisabeth

      ;

      Ruet, Aurelie

      ;

      Labauge, Pierre

      ;

      Zephir, Helene

      ;

      Kwiatkowski, Arnaud

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      van der Walt, Anneke

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      Kalincik, Tomas

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      Butzkueven, Helmut

      2025

      ,

      Journal of Neurology, Neurosurgery and Psychiatry

      ,

      96

      (6)

      Background: Effectiveness of disease-modifying treatment (DMT) in people affected by primary progressive multiple sclerosis (PPMS) is limited. Whether specific subgroups may benefit more from DMT in a real-world setting ...

    • Acute polyneuropathy: a serious complication of levodopa/ /carbidopa intestinal gel treatment for Parkinson's Disease 

      original article

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      Havránková, Petra

      ;

      Roth, Jan

      ;

      Čapek, Václav

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      Klempíř, Jiří

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      Baláž, Marek

      ;

      Rektorová, Irena

      ;

      Haň, Vladimír

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      Skorvanek, Matej

      ;

      Gmitterová, Karin

      ;

      Minár, Michal

      ;

      Valkovič, Peter

      ;

      Kaiserová, Michaela

      ;

      Kaňovský, Petr

      ;

      Grofik, Milan

      ;

      Kurča, Egon

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      Necpál, Ján

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      Jech, Robert

      2024

      ,

      Termedia

      ,

      Neurologia i Neurochirurgia Polska

      ,

      58

      (6)

      Aim of study. To determine whether a high dose of levodopa-carbidopa intestinal gel (LCIG), expressed as levodopa equivalent daily dose (LE daily dose), is a risk factor for acute polyneuropathy in patients treated with ...

    • Lurcher Mouse as a Model of Cerebellar Syndromes 

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      Roy Choudhury, Nilpawan

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      Hilber, Pascal

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      Cendelín, Jan

      2025

      ,

      The Cerebellum

      ,

      24

      (2)

      Cerebellar extinction lesions can manifest themselves with cerebellar motor and cerebellar cognitive affective syndromes. For investigation of the functions of the cerebellum and the pathogenesis of cerebellar diseases, ...

    • Anatomical biliary reconstruction as an ultimum refugium for selective cases-History and current state of knowledge 

      summarizing article

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      Ševčík, Jan

      ;

      Massaro, Maria Stefania

      ;

      Pálek, Richard

      ;

      Moulisová, Vladimíra

      ;

      Liška, Václav

      2024

      ,

      Journal of Hepato-Biliary-Pancreatic Sciences

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      31

      (11)

      Reconstruction of extrahepatic bile ducts is a staple procedure of HPB surgery. The current standard for most cases is a nonanatomical bilioenteric reconstruction, a satisfactory option for the majority of patients. However, ...

    • Effects of overcoming isometric unilateral conditioning activity on subsequent single-leg drop jump in elite and amateur volleyball players: a randomized crossover trial 

      original article

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      Terbalyan, Artur

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      Mikolajec, Kazimierz

      ;

      Krzysztofik, Michal

      ;

      Urbanski, Robert

      ;

      Jarosz, Jakub

      ;

      Šťastný, Petr

      ;

      Spieszny, Michal

      2025

      ,

      BioMed Central

      ,

      BMC Sports Science, Medicine and Rehabilitation

      ,

      17

      (1)

      Background The study aimed to assess the acute effects of overcoming isometric split squats on subsequent single-leg drop jump (DJ) performance and the contralateral effect in volleyball players, considering training status ...

    • The development of L. major, L. donovani and L. martiniquensis, Leishmania currently emerging in Europe, in the sand fly species Phlebotomus perniciosus and P. tobbi 

      original article

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      Sádlová, Jovana

      ;

      Hošková, Anna

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      Vojtková, Barbora

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      Bečvář, Tomáš

      ;

      Volf, Petr

      2024

      ,

      PLoS Neglected Tropical Diseases

      ,

      18

      (10)

      Background: Several new species of Leishmania have recently emerged in Europe, probably as the result of global changes and increased human migration from endemic areas. In this study, we tested whether two sand fly species, ...

    • Microplastics originated from agricultural mulching films affect enchytraeid multigeneration reproduction and soil properties 

      original article

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      Šmídová, Klára

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      Selonen, Salla

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      van Gestel, Cornelis A. M.

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      Fleissig, Petr

      ;

      Hofman, Jakub

      2024

      ,

      Journal of Hazardous Materials

      ,

      479

      (November)

      Microplastics (MPs) are increasingly entering agricultural soils, often from the breakdown of agricultural plastics (e.g., mulching films). This study investigates the effects of realistic MPs from different mulching films: ...

    • Spatial immune heterogeneity in a mouse tumor model after immunotherapy 

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      Šmahel, Michal

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      Johari, Shweta Dilip

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      Šmahelová, Jana

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      Pfeiferová, Lucie

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      Nunvář, Jaroslav

      2025

      ,

      Cancer Science

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      116

      (3)

      Cancer immunotherapy is increasingly used in clinical practice, but its success rate is reduced by tumor escape from the immune system. This may be due to the genetic instability of tumor cells, which allows them to adapt ...

    • Exploring vulnerability amplification in regional health inequality: COVID-19 case study in Czechia 

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      Netrdová, Pavlína

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      Hulíková Tesárková, Klára

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      Dzúrová, Dagmar

      2025

      ,

      Applied Geography

      ,

      177

      (April)

      This paper proposes a novel conceptual framework of vulnerability amplification to examine regional health inequalities. It combines differential vulnerability in health and social amplification of risk, as mechanisms of ...

    • Srovnávací pedagogika jako cesta ke zkvalitňování profesní přípravy učitelů v předškolním vzdělávání 

      Comparative pedagogy as a way to improve the professional training of pre-school teachers

      abstract in conference proceedings

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      Uhlířová, Jana

      ;

      Loudová Stralczynská, Barbora

      2024

      ,

      Česká asociace pedagogického výzkumu

      ,

      SPOLUPRÁCE OBORŮ PRO PODPORU KVALITY VZDĚLÁVÁNÍ

      Příspěvek mapuje rozvoj výuky srovnávací pedagogiky v oblasti předškolního vzdělávání na Pedagogické fakultě Univerzity Karlovy. Cílem je analyzovat rozvoj komparativní tematiky v obsazích programů učitelství pro MŠ (Bc.) ...

    • Azadirachtin disrupts ecdysone signaling and alters sand fly immunity 

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      Stahl Vieira, Cecilia

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      Bisogno, Sara

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      Salvemini, Marco

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      Loza Telleria, Erich

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      Volf, Petr

      2024

      ,

      BioMed Central

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      Parasites & Vectors

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      17

      (1)

      Background: Leishmaniasis is a group of neglected vector-borne diseases transmitted by phlebotomine sand flies. Leishmania parasites must overcome various defenses in the sand fly midgut, including the insects's immune ...

    • „Nauka o lyofilizovaných jahodách“ aneb Náčrt historie Katedry vysoké frekvence a vakuové techniky (1953–1959) a Katedry elektroniky a vakuové fyziky (1959–1989) Matematicko-fyzikální fakulty Univerzity Karlovy 

      ‘The Theory of Lyophilised Strawberries’ or The History of the Department of High Frequencies and Vacuum Technology (1953–1959) and the Department of Electronics and Vacuum Physics (1959–1989) of the Faculty of Mathematics and Physics of the Charles University

      original article

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      Brčák, Marek

      2024

      ,

      Acta Universitatis Carolinae. Historia Universitatis Carolinae Pragensis

      ,

      2024

      (1)

      Studie se zabývá historií Katedry fyziky povrchů a plazmatu Matematicko-fyzikální fakulty Univerzity Karlovy, která si v akademickém roce 2023/2024 připomíná 70 let od svého založení, přičemž během své existence dvakrát ...

    • Martin Musílek (ed.), Ceny – mzdy – peníze: Ekonomické myšlení ve středověkých a raně novověkých městech, Praha 2023 

      Martin Musílek (ed.), Prices - wages - money: economic thinking in medieval and early modern cities, Prague 2023

      review

      open access

      published version

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      Boukal, Jan

      2024

      ,

      Acta Universitatis Carolinae. Historia Universitatis Carolinae Pragensis

      ,

      64

      (1)

      Recenze na knihu: Martin Musílek (ed.), Ceny - mzdy - peníze: Ekonomické myšlení ve středověkých a raně novověkých městech, Argo, Praha 2023, 368 s., ISBN 978-80-257-4062-0

    • Jaroslav Bidlo (1868–1937) a Milada Paulová (1891–1970). Bibliografie publikovaných prací 

      Jaroslav Bidlo (1868–1937) and Milada Paulová (1891–1970). Bibliography of published works

      collective monograph

      restricted access

      published version

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      Ďurčanský, Marek

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      Urbanová, Jiřina

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      Boháček, Jan

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      Brádlerová, Daniela

      2024

      ,

      Praha

      ,

      Národní knihovna ČR - Slovanská knihovna

      Jaroslav Bidlo (1868-1937) a Milada Paulová (1891-1970) patří mezi zakladatelské osobnosti české historické slavistiky. Jejich přínos k poznání dějin východní a středovýchodní Evropy zatím nemohl být plně doceněn. Z jejich ...

    • Nestor české medicíny. Profesor Bohumil Eiselt mezi univerzitou, lékařskou vědou a emancipačními snahami Čechů v habsburské monarchii 

      The Nestor of Czech Medicine: Professor Bohumil Eiselt between the University, Medical Science, and Emancipation Efforts of the Czechs in the Habsburg Monarchy

      summarizing article

      open access

      published version

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      Boukal, Jan

      2024

      ,

      Acta Universitatis Carolinae. Historia Universitatis Carolinae Pragensis

      ,

      64

      (1)

      Článek se zabývá životem a dílem Bohumila Eiselta (1831-1908), lékaře a univerzitního profesora. Na rozdíl od dřívějších biografií, které se opíraly převážně o jeho vlastní paměti, se tento text zaměřuje na Eiseltovu roli ...

    • Korespondencja Jana Karola Kochanowskiego z Jaroslavem Bidlem z lat 1902-1920 

      Correspondence of Jan Karol Kochanowski with Jaroslav Bidlo from the years 1902-1920

      original article

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      Biliński, Piotr

      ;

      Ďurčanský, Marek

      2022

      ,

      Klio Polska

      ,

      14

      (Neuveden)

      Część artykułu stanowi studia biograficzna o polskim historyku Janie Karolu Kochanowskim (1869-1949) i jego kontaktach z historykiem czeskim Jaroslavem Bidlo (1868-1937). Studię uzupełnia edycja 18 listów z ich wzajemnej ...

    • Cultural Memory in the Icelandic Contemporary Sagas : Constructing Continuity at a Time of Transformation 

      monograph

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      published version

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      Korecká, Lucie

      2025

      ,

      Berlin

      ,

      Walter de Gruyter GmbH

      The objective of this book is to analyse the Old Icelandic sagas dealing with the twelfth to fourteenth centuries - the secular contemporary sagas and the bishops' sagas - from the perspective of cultural memory studies. ...

    • The interactions between monocarboxylate transporter genes MCT1, MCT2, and MCT4 and the kinetics of blood lactate production and removal after high-intensity efforts in elite males: a cross-sectional study 

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      Maculewicz, Ewelina

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      Mastalerz, Andrzej

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      Garbacz, Aleksandra

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      Mroz, Anna

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      Šťastný, Petr

      ;

      Petr, Miroslav

      ;

      Kolinger, Dominik

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      Vostatková, Pavlína

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      Bojarczuk, Aleksandra

      2025

      ,

      BioMed Central

      ,

      BMC Genomics

      ,

      26

      (1)

      BackgroundThis cross-sectional study investigated the relationship between genetic variations in monocarboxylate transporter genes and blood lactate production and removal after high-intensity efforts in humans. The study ...

    • Auer rod-positive acute leukemia with predominantly lymphoid immunophenotype: Report on 11 cases and review of literature 

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      Hrušák, Ondřej

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      Stančíková, Jitka

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      Vodičková, Elena

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      Podolská, Tereza

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      Möricke, Anja

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      Attarbaschi, Andishe

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      Dworzak, Michael

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      Šestáková, Zuzana

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      Švec, Peter

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      Kubričanová Žaliová, Markéta

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      Janotová, Iveta

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      Zapletal, Ondřej

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      Mejstříková, Ester

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      Starý, Jan

      2025

      ,

      John Wiley

      ,

      Pediatric Blood and Cancer

      ,

      72

      (1)

      BACKGROUND: Auer rods (AuRs) are prominent intracellular structures found almost exclusively in myeloid cell malignancies, such as acute myeloid leukemia (AML), chronic and juvenile myelomonocytic leukemia and myelodysplastic ...

    • Optical fibre long-period grating sensors modified with antifouling bio-functional nano-brushes 

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      Vrabcová, Markéta

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      Spasovová, Monika

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      Forinová, Michala

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      Giannetti, Ambra

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      Houska, Milan

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      Lynn Jr, N. Scott

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      Baldini, Francesco

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      Kopecek, Jaromir

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      Chiavaioli, Francesco

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      Vaisocherova-Lisalova, Hana

      2025

      ,

      Biomaterials Science

      ,

      13

      (5)

      Recent advances in optical sensing technologies underpin the development of high-performance, surface-sensitive analytical tools capable of reliable and precise detection of molecular targets in complex biological media ...