Repozitář publikační činnosti UK: Poslední příspěvky
Zobrazují se záznamy 1461-1480 z 1854
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Changes in reproductive behavior associated with the perception and individual experiences of the COVID-19 pandemic
původní článek
embargo
vydavatelská verze
2023
,PLoS One
,18
(7)
This study evaluates the impacts of the COVID-19 pandemic on the reproductive behavior of men and women during the most restrictive period of the pandemic in Czechia. At the end of this period, data was collected for the ...
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Mouse PML protein isoforms and their role in Mouse Polyomavirus infection
abstrakt v konferenčním sborníku
open access
preprint
2023
,Praha
,WBW 2023 Book of Abstracts
Promyelocytic leukaemia nuclear bodies (PML NBs) are dynamic, spherical, membrane-less structures composed of the main scaffold PML protein and a variety of stable or transient partner proteins. Apart from many endogenous ...
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Mouse Polyomavirus Affects Nuclear Lamina in the Late Phase of Infection
abstrakt v konferenčním sborníku
open access
preprint
2023
,WBW 2023 Book of Abstracts
One of the important components of nuclear cytoskeleton is nuclear lamina. It is composed of intermediate filaments V, A type lamins (lamin A/C) and B type lamins (lamin B1 and B2). Although nuclear lamina maintains the ...
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Regulation of Phenolic Compound Production by Light Varying in Spectral Quality and Total Irradiance
původní článek
open access
vydavatelská verze
2022
,International Journal of Molecular Sciences
,23
(12)
Photosynthetically active radiation (PAR) is an important environmental cue inducing the production of many secondary metabolites involved in plant oxidative stress avoidance and tolerance. To examine the complex role of ...
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Antimycobacterial pyridine carboxamides: From design to in vivo activity
původní článek
embargo
vydavatelská verze
2023
,European Journal of Medicinal Chemistry
,258
(October)
Tuberculosis is the number one killer of infectious diseases caused by a single microbe, namely Mycobacterium tuberculosis (Mtb). The success rate of curing this infection is decreasing due to emerging antimicrobial ...
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Prevalence of Dual Diagnoses among Children and Adolescents with Mental Health Conditions
původní článek
embargo
vydavatelská verze
2023
,Children-Basel [online]
,10
(2)
Background: The World Health Organisation defines dual diagnosis as the co-occurrence in the same individual of a psychoactive substance use disorder and another psychiatric disorder. Children and adolescents with dual ...
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Primary assessment of medicines for expected migrastatic potential with holographic incoherent quantitative phase imaging
původní článek
open access
vydavatelská verze
2023
,Biomedical Optics Express
,14
(6)
Solid tumor metastases cause most cancer-related deaths. The prevention of their occurrence misses suitable anti-metastases medicines newly labeled as migrastatics. The first indication of migrastatics potential is based ...
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Serum Metabolite Biomarkers for Pancreatic Tumors: Neuroendocrine and Pancreatic Ductal Adenocarcinomas-A Preliminary Study
původní článek
open access
vydavatelská verze
2023
,Cancers
,15
(12)
BACKGROUND: Pancreatic cancer is the most common pancreatic solid malignancy with an aggressive clinical course and low survival rate. There are a limited number of reliable prognostic biomarkers and a need to understand ...
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DNA Repair Pathway in Ovarian Cancer Patients Treated with HIPEC
původní článek
open access
vydavatelská verze
2023
,International Journal of Molecular Sciences
,24
(10)
DNA repair pathways are essential for maintaining genome stability, and understanding the regulation of these mechanisms may help in the design of new strategies for treatments, the prevention of platinum-based chemoresistance, ...
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Mediálny obraz hromadného posadnutia v Morzine v rakúskej tlači
Interpretation of the mass possession in Morzine by contemporary Austrian press
původní článek
open access
vydavatelská verze
2022
,Theatrum historiae
,17
(30)
Štúdia sa zameriava na hromadné posadnutie v Morzine v polovici 19. storočia. Hlavným cieľom je analyzovať reflexiu posadnutia dobovými médiami. V novinových článkoch sme identifikovali 6 diskurzov. V prvom môžeme vidieť ...
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2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1
původní článek
embargo
vydavatelská verze
2023
,European Journal of Medicinal Chemistry
,258
(October)
Phenotypic screening of an in-house library of small molecule purine derivatives against Mycobacterium tuberculosis (Mtb) led to the identification of 2-morpholino-7-(naphthalen-2-ylmethyl)-1,7-dihydro-6H-purin-6-one 10 ...
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Contagious Defaults in Interbank Networks
původní článek
embargo
vydavatelská verze
2022
,Finance a úvěr
,72
(2)
This paper investigates systemic risk and contagion processes in an interbank network using network science methods. The interbank network is studied to understand the contagion process within a network considering differences ...
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You like it, you learn it: affectivity and learning in competitive social role play gaming
původní článek
omezený přístup
vydavatelská verze
2016
,International Journal of Computer-Supported Collaborative Learning
,11
(3)
Despite the alleged ability of digital game-based learning (DGBL) to foster positive affect and in turn improve learning, the link between affectivity and learning has not been sufficiently investigated in this field. ...
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Editorial: Mobile genetic elements as dissemination drivers of multidrug-resistant Gram-negative bacteria
jiný článek
embargo
vydavatelská verze
2023
,Frontiers in Cellular and Infection Microbiology
,13
(March)
Mobile genetic elements as dissemination drivers of multidrug-resistant Gram-negative bacteria - no abstract available
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Gut Microbiome Diversity of Porcine Peritonitis Model of Sepsis
abstrakt v konferenčním sborníku
embargo
vydavatelská verze
2022
,Czech Chemical Society Symposium Series
,20
(6)
Animal models are essential in understanding of the mechanisms of sepsis moreover the development and the assessment of emerging therapies. In clinically relevant porcine model, however, a significant ...
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Survival in Lung Cancer in the Nordic Countries Through A Half Century
původní článek
embargo
vydavatelská verze
2023
,Clinical Epidemiology
,15
(May)
Objective: Lung cancer is often diagnosed at an advanced stage and survival has been poor, although long-term studies have been rare. We analyzed data on survival in lung cancer from Denmark, Finland, Norway, and Sweden ...
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Survival in melanoma in the nordic countries into the era of targeted and immunological therapies
původní článek
embargo
vydavatelská verze
2023
,European Journal of Cancer
,186
(June)
Objectives: Survival in melanoma has been increasing and the most recent interest is to observe the population-level impact of novel targeted therapies and immunotherapy. We analysed survival in melanoma from Denmark (DK), ...
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The dynamics of telomere length in primary and metastatic colorectal cancer lesions
původní článek
embargo
vydavatelská verze
2023
,Scientific Reports
,13
(1)
Telomeric sequences, the structures comprised of hexanucleotide repeats and associated proteins, play a pivotal role in chromosome end protection and preservation of genomic stability. Herein we address telomere length ...
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Preferred β-lactone synthesis can explain high rate of false-negative results in the detection of OXA-48-like carbapenemases
abstrakt v konferenčním sborníku
embargo
vydavatelská verze
2022
,Czech Chemical Society Symposium Series
,20
(6)
The resistance to carbapenems is usually mediated by enzymes hydrolyzing β-lactam ring. Recently, an alternative way of the modification of the antibiotic, a β-lactone formation by OXA-48-like enzymes, in some carbapenems ...
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Epidemic spread of KPC-producing bacteria in the Czech Republic
abstrakt v konferenčním sborníku
embargo
vydavatelská verze
2022
,Czech Chemical Society Symposium Series
,20
(6)
Carbapenems are currently last-resort antibiotics for the therapy of infections caused by multidrug-resistant Gram-negative bacteria. Therefore, the resistence to those drugs represents a significant threat of current ...
