| dc.contributor.author | Vopálenský, Václav | |
| dc.contributor.author | Sýkora, Michal | |
| dc.contributor.author | Mělková, Zora | |
| dc.contributor.author | Barvík, Ivan | |
| dc.contributor.author | Mašek, Tomáš | |
| dc.contributor.author | Horáčková, Kamila | |
| dc.contributor.author | Pospíšek, Martin | |
| dc.contributor.editor | Šímová, Šárka | |
| dc.date.accessioned | 2023-11-03T13:10:30Z | |
| dc.date.available | 2023-11-03T13:10:30Z | |
| dc.date.issued | 2023 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14178/2061 | |
| dc.description.abstract | The Vaccinia virus (VACV) played a pivotal role in the discovery of the 5' mRNA. Over the past decades, VACV investigation has contributed extensively to understanding the mechanism behind 5' mRNA cap synthesis. In this study, we conducted a comprehensive analysis of VACV transcripts at the level of individual mRNA molecules. Surprisingly, our findings reveal that postreplicative VACV mRNAs, which incorporate nontemplated 5' poly(A) leaders, lack the conventional 5' cap structure in vivo. | en |
| dc.language.iso | en | |
| dc.relation.url | http://www.ccsss.cz/index.php/ccsss/issue/view/41/ | |
| dc.rights | Creative Commons Uveďte původ 4.0 International | cs |
| dc.rights | Creative Commons Attribution 4.0 International | en |
| dc.title | Absence of 5' methylguanosine cap in postreplicative genes' transcripts of Vaccinia virus | en |
| dcterms.accessRights | openAccess | |
| dcterms.license | https://creativecommons.org/licenses/by/4.0/legalcode | |
| dc.date.updated | 2024-01-02T10:40:42Z | |
| dc.subject.keyword | 5' mRNA | en |
| dc.subject.keyword | VACV | en |
| dc.relation.fundingReference | info:eu-repo/grantAgreement/MSM//LX22NPO5103 | |
| dc.date.embargoStartDate | 2024-01-02 | |
| dc.type.obd | 110 | |
| dc.type.version | info:eu-repo/semantics/acceptedVersion | |
| dc.identifier.obd | 637741 | |
| dc.subject.rivPrimary | 10000::10600 | |
| dcterms.isPartOf.name | Czech Chemical Society Symposium Series | |
| dcterms.isPartOf.issn | 2336-7202 | |
| dcterms.isPartOf.journalYear | 2023 | |
| dcterms.isPartOf.journalVolume | 21 | |
| dcterms.isPartOf.journalIssue | 5 | |
| uk.faculty.primaryId | 115 | |
| uk.faculty.primaryName | Přírodovědecká fakulta | cs |
| uk.faculty.primaryName | Faculty of Science | en |
| uk.faculty.secondaryId | 108 | |
| uk.faculty.secondaryId | 116 | |
| uk.faculty.secondaryName | 1. lékařská fakulta | cs |
| uk.faculty.secondaryName | First Faculty of Medicine | en |
| uk.faculty.secondaryName | Matematicko-fyzikální fakulta | cs |
| uk.faculty.secondaryName | Faculty of Mathematics and Physics | en |
| uk.department.primaryId | 1034 | |
| uk.department.primaryName | Katedra genetiky a mikrobiologie | cs |
| uk.department.primaryName | Department of Genetics and Microbiology | en |
| uk.department.secondaryId | 1191 | |
| uk.department.secondaryId | 1539 | |
| uk.department.secondaryName | Fyzikální ústav UK | cs |
| uk.department.secondaryName | Institute of Physics of Charles University | en |
| uk.department.secondaryName | Ústav imunologie a mikrobiologie 1. LF UK a VFN | cs |
| uk.department.secondaryName | Institute of Immunology and Microbiology | en |
| uk.event.name | The second annual meeting of the National Institute of Virology and Bacteriology (NIVB Meeting 2023| | |
| dc.description.pageRange | 230-230 | |
| dc.type.obdHierarchyCs | ABSTRAKT::abstrakt::abstrakt v konferenčním sborníku | cs |
| dc.type.obdHierarchyEn | ABSTRACT::abstract::abstract in conference proceedings | en |
| dc.type.obdHierarchyCode | 110::130::462 | en |
| uk.displayTitle | Absence of 5' methylguanosine cap in postreplicative genes' transcripts of Vaccinia virus | en |
