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Chimeric JAK2 Kinases Trigger Non-uniform Changes of Cellular Metabolism in BCR-ABL1-like Childhood ALL

dc.contributor.authorLukeš, Julius
dc.contributor.authorPotůčková, Eliška
dc.contributor.authorAlquezar Artieda, Natividad
dc.contributor.authorHeřmanová, Ivana
dc.contributor.authorKosanovic, Sladjana
dc.contributor.authorHložková, Kateřina
dc.contributor.authorAlberich Jorda, Meritxell
dc.contributor.authorZuna, Jan
dc.contributor.authorTrka, Jan
dc.contributor.authorTennant, Daniel A
dc.contributor.authorStanulla, Martin
dc.contributor.authorŽaliová, Markéta
dc.contributor.authorStarková, Júlia
dc.date.accessioned2023-12-13T13:10:37Z
dc.date.available2023-12-13T13:10:37Z
dc.date.issued2023
dc.identifier.urihttps://hdl.handle.net/20.500.14178/2120
dc.description.abstractWe studied the impact of JAK2 fusions on metabolic rewiring of leukemic cells; we chose two representatives, themost frequent fusion and a novel previously undescribed fusion, and we showed that JAK2 fusions indeed alter energy metabolism of leukemic cells, but surprisingly in a very distinct manner.en
dc.language.isoen
dc.relation.urlhttps://doi.org/10.1097/HS9.0000000000000946
dc.rightsCreative Commons Uveďte původ 4.0 Internationalcs
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.titleChimeric JAK2 Kinases Trigger Non-uniform Changes of Cellular Metabolism in BCR-ABL1-like Childhood ALLen
dcterms.accessRightsopenAccess
dcterms.licensehttps://creativecommons.org/licenses/by/4.0/legalcode
dc.date.updated2023-12-13T13:10:37Z
dc.subject.keywordChimeric JAK2en
dc.subject.keywordCellular Metabolismen
dc.subject.keywordBCR-ABL1-like Childhood ALLen
dc.relation.fundingReferenceinfo:eu-repo/grantAgreement/MZ0/NU/NU22-07-00087
dc.relation.fundingReferenceinfo:eu-repo/grantAgreement/GA0/GA/GA20-27132S
dc.relation.fundingReferenceinfo:eu-repo/grantAgreement/FN/I-FN/I-FNM
dc.relation.fundingReferenceinfo:eu-repo/grantAgreement/MSM//LX22NPO5102
dc.date.embargoStartDate2023-12-13
dc.type.obd73
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.doi10.1097/HS9.0000000000000946
dc.identifier.utWos001055544000004
dc.identifier.eidScopus2-s2.0-85170417193
dc.identifier.obd634711
dc.identifier.pubmed37637992
dc.subject.rivPrimary30000::30200::30205
dc.subject.rivSecondary30000::30200::30204
dcterms.isPartOf.nameHemaSphere
dcterms.isPartOf.issn2572-9241
dcterms.isPartOf.journalYear2023
dcterms.isPartOf.journalVolume7
dcterms.isPartOf.journalIssue9
uk.faculty.primaryId109
uk.faculty.primaryName2. lékařská fakultacs
uk.faculty.primaryNameSecond Faculty of Medicineen
uk.faculty.secondaryId52
uk.faculty.secondaryNameFakultní nemocnice v Motolecs
uk.faculty.secondaryNameMotol University Hospitalen
uk.department.primaryId109
uk.department.primaryName2. lékařská fakultacs
uk.department.primaryNameSecond Faculty of Medicineen
uk.department.secondaryId1675
uk.department.secondaryId100010692507
uk.department.secondaryNameKlinika dětské hematologie a onkologiecs
uk.department.secondaryNameKlinika dětské hematologie a onkologieen
uk.department.secondaryNameKlinika dětské hematologie a onkologie 2. LF UK a FN Motolcs
uk.department.secondaryNameDepartment of Paediatric Haematology and Oncology, 2nd Faculty of Medicine and Motol University Hosen
dc.type.obdHierarchyCsČLÁNEK V ČASOPISU::článek v časopisu::letter to the editorscs
dc.type.obdHierarchyEnJOURNAL ARTICLE::journal article::letter to the editorsen
dc.type.obdHierarchyCode73::152::233en
uk.displayTitleChimeric JAK2 Kinases Trigger Non-uniform Changes of Cellular Metabolism in BCR-ABL1-like Childhood ALLen


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