Přírodovědecká fakulta
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Poslední příspěvky
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The biomolecular markers for the personalized prediction of the treatment effect in patients with head and neck cancer: pilot study
abstrakt v elektronické podobě
open access
postprint
2024
,Edinburgh
R42 Anotace anglickyThe clinical utility of liquid biopsies as diagnostic, predictive and prognostic biomarkers has been shown for several cancers. Our study analyses the dynamics of human papillomavirus (HPV) cell cell-free ...
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Effect of the ADAR1 signalling pathway on HCV replication
abstrakt v elektronické podobě
open access
postprint
2024
,Edinburgh
,RNA 2024
The hepatitis C virus (HCV) is a member of the Flaviviridae family whose genome consists of a +RNAmolecule. Although new direct-acting antivirals (DAAs) are highly effective in treating hepatitis C, tens ofmillions of ...
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Performance in the recruitment life stage and its potential contribution to invasive success in the polyploid invader Centaurea stoebe
původní článek
open access
vydavatelská verze
2024
,NeoBiota
,95
(17.10.2024)
The recruitment life stage, including germination and early seedling establishment, is the most vulnerable life stage of plants and has cascading effects on plant performance at later life stages. However, surprisingly ...
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Herbarium specimens reveal a cryptic invasion of polyploid Centaurea stoebe in Europe
původní článek
open access
vydavatelská verze
2025
,New Phytologist
,245
(1)
Numerous plant species are expanding their native ranges due to anthropogenic environmental change. Because cytotypes of polyploid complexes often show similar morphologies, there may be unnoticed range expansions (i.e. ...
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Polysome profiling of Cell Cycle
abstrakt v elektronické podobě
open access
postprint
2024
,Edinburgh
,RNA 2024
mRNA Translation is a highly regulated process and even more so during cell cycle transition where andthe activation or degradation of proteins mediate progression through the various phases of the cellcycle. In numerous ...
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Asaia bacteria in sand flies and their impact on Leishmania transmission
abstrakt v konferenčním sborníku
open access
postprint
2024
,Koper, Slovenia
,University of Primorska Press
,ISOPS XI: International Symposium on Phlebotomine Sandflies, 9-13 September 2024, Portorož, Slovenia : Programme and Abstract Book
Midgut microbiome was demonstrated to affect the transmission of vector-borne pathogens. In sandflies, Asaia bacteria was found as a part diet and midgut microbiome. Here, we have investigated theeffect of two Asaia species ...
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Susceptibility of various sand fly species to Toscana virus
abstrakt v konferenčním sborníku
open access
postprint
2024
,Koper, Slovenia
,University of Primorska Press
,ISOPS XI: International Symposium on Phlebotomine Sandflies, 9-13 September 2024, Portorož, Slovenia : Programme and Abstract Book
Phlebotomine sand flies transmit numerous viral pathogens, including Toscana virus (TOSV,Phenuiviridae). This arbovirus is spread in the Mediterranean area and causes a wide range of clinicalsymptoms (from non-symptomatic ...
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Zeolite-catalyzed one-pot sucrose-to-HMF transformation: Ge outperforms Sn, Zr, and Al sites
původní článek
open access
preprint
2024
,Microporous and Mesoporous Materials
,378
(October)
The conversion of renewable compounds to versatile platform molecules over environmentally friendly heterogeneous catalysts is a major challenge. Zeolites stand as active, selective, and reusable solid catalysts for various ...
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Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways
původní článek
open access
vydavatelská verze
2024
,eLife
,13
(November)
Protein synthesis plays a major role in homeostasis and when dysregulated leads to various pathologies including cancer. To this end, imbalanced expression of eukaryotic translation initiation factors (eIFs) is not only a ...
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Vaccination and fertility: modelling the potential impact of Covid-19 vaccination on total fertility rate in Czechia
původní článek
open access
vydavatelská verze
2024
,Genus
,80
(4. prosince 2024)
As with Northern European countries, Czechia experienced unexpected fertility developments during the Covid-19 pandemic. Fertility in Czechia increased between 2020 and 2021 from 1.76 children per woman to 1.83. However, ...
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Microtubule-associated NAV3 regulates invasive phenotypes in glioblastoma cells
původní článek
open access
vydavatelská verze
2025
,Brain Pathology
,35
(1)
Glioblastomas are aggressive brain tumors for which effective therapy is still lacking, resulting in dismal survival rates. These tumors display significant phenotypic plasticity, harboring diverse cell populations ranging ...
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Incorporating high-resolution climate, remote sensing and topographic data to map annual forest growth in central and eastern Europe
původní článek
open access
vydavatelská verze
2024
,Science of the Total Environment
,913
(February)
To enhance our understanding of forest carbon sequestration, climate change mitigation and drought impact on forest ecosystems, the availability of high-resolution annual forest growth maps based on tree-ring width (TRW) ...
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Local diversity of soil forming processes in the semi-arid tropics and its environmental drivers: An example from Otavi Mountains, northern Namibia
původní článek
open access
vydavatelská verze
2025
,Catena
,249
(February)
Local diversity of soil units and properties in a semi-arid tropical climate is controlled by a number of interacting factors, whose contribution to the final form of individual soil characteristics is often difficult to ...
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Arsenic bioaccessibility in environmentally important arsenic minerals
původní článek
open access
vydavatelská verze
2025
,Journal of Hazardous Materials
,485
(March)
The potential risk to humans from incidental ingestion of As-contaminated soil and mine waste is influenced by the mineralogical composition of the As phases present. Using the Solubility Bioaccessibility Research Consortium ...
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Mouse polyomavirus infection induces lamin reorganisation
původní článek
open access
vydavatelská verze
2024
,FEBS Journal
,291
(23)
The nuclear lamina is a dense network of intermediate filaments beneath the inner nuclear membrane. Composed of A-type lamins (lamin A/C) and B-type lamins (lamins B1 and B2), the nuclear lamina provides a scaffold for the ...
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Italian peninsula as a hybridization zone of Ixodes inopinatus and I. ricinus and the prevalence of tick-borne pathogens in I. inopinatus, I. ricinus, and their hybrids
původní článek
open access
vydavatelská verze
2024
,Parasites & Vectors
,17
(1)
BACKGROUND: Ixodes inopinatus was described from Spain on the basis of morphology and partial sequencing of 16S ribosomal DNA. However, several studies suggested that morphological differences between I. inopinatus and ...
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Toscana virus – finding the new vectors
jiný příspěvek v konferenčním sborníku
open access
vydavatelská verze
2024
,New Orleans
,American Society of Tropical Medicine and Hygiene
,ASTMH Abstract Book 2024
,2024
Arbovirus Phlebovirus toscanaense (TOSV) is an emerging but still neglected human pathogen that circulates in countries around the Mediterranean Sea. The manifestation of the disease varies from non-symptomatic forms through ...
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Mouse PML protein isoforms and their role in innate antiviral immunity
abstrakt v elektronické podobě
open access
postprint
2024
Promyelocytic leukaemia nuclear bodies (PML NBs) are dynamic, multiprotein, membrane-less structures composed of the main scaffold PML protein and various stable or transient partner proteins. Beyond their diverse endogenous ...
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ASPH inhibition reveals differential gene expression patterns in HPV-positive and HPV-negative cell lines
abstrakt v elektronické podobě
open access
preprint
2024
,Boston
Cancer is associated with alterations in key cellular pathways, including the aspartate β-hydroxylase (ASPH) pathway. ASPH is an oncogene upregulated in various carcinomas, playing a vital role in tumor progression and ...
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HPV Infection: Present and Future of Diagnostic and Prognostic Surveys
abstrakt v elektronické podobě
open access
postprint
2024
High-risk types of Human Papillomavirus (HPV) are closely associated with various human malignancies. The ability to detect precancerous stages early significantly impacts patient outcomes, yet challenges remain in the ...
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