The Czech Home Parenteral Nutrition Registry REDNUP: Comprehensive Analysis of Adult Patients' Data

Autor
Koudelková, Kateřina
Wohl, Petr
Šenkyřík, Michal
Beneš, Petr
Vejmelka, Jiří
Maňák, Jan
Těšínský, Pavel
Datum vydání
2024Publikováno v
Annals of Nutrition & MetabolismRočník / Číslo vydání
80 (3)ISBN / ISSN
ISSN: 0250-6807ISBN / ISSN
eISSN: 1421-9697Metadata
Zobrazit celý záznamTato publikace má vydavatelskou verzi s DOI 10.1159/000538232
Abstrakt
INTRODUCTION: Home parenteral nutrition (HPN) is the primary treatment modality for patients with chronic intestinal failure, one of the least common organ failures. This article provides a retrospective analysis of the data collected on HPN patients in the Czech Republic over the past 30 years. METHODS: National registry data was collected using a standardised online form based on the OASIS registry (Oley-A.S.P.E.N. Information System) across all centres providing HPN in the Czech Republic. Data collected prospectively from adult patients in the HPN program was analysed in the following categories: epidemiology, demographics, underlying syndrome, and diagnosis, complications, and teduglutide therapy prevalence. RESULTS: The registry identified a total of 1,838 adult patient records, reflecting almost 1.5 million individual catheter days. The prevalence of HPN has risen considerably over the last few decades, currently reaching 5.5 per 100,000 population. The majority of patients have short bowel syndrome and GI obstruction, with cancer being the most prevalent underlying disease. Catheter-related bloodstream infections have been the most prevalent acute complication. However, the incidence in 2022 was only 0.15 per 1,000 catheter days. The study also observed an increase in the prevalence of patients on palliative HPN over the last decade. CONCLUSION: This study presents a thorough analysis of data from the Czech REDNUP registry. It shows an increasing prevalence of HPN, namely in the palliative patient group. The sharing of national data can improve understanding of this rare condition and facilitate the development of international guidelines.
Klíčová slova
home parenteral nutrition, chronic intestinal failure, national registry, epidemiology
Trvalý odkaz
https://hdl.handle.net/20.500.14178/2541Licence
Licence pro užití plného textu výsledku: Creative Commons Uveďte původ 4.0 International