Faculty of Science: Recent submissions
Now showing items 41-60 of 209
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Vliv socioekonomického statusu na výskyt depresivních symptomů v populaci Česka – výsledky EHIS 2019
The Effect of Socioeconomic Status on the Occurrence of Depressive Symptoms in the Czech Population-Ehis 2019 Results
original article
embargoed access
published version
2023
,Demografie
,65
(2)
Tato práce zkoumá vliv socioekonomických faktorů (včetně dosaženého stupně dosaženého vzdělání, ekonomické aktivity a příjmu) na výskyt symptomů deprese v české populaci. Analýzy vycházejí z průřezového European Health ...
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Aspartate β-hydroxylase Regulates Expression of Ly6 Genes
original article
open access
published version
2024
,Journal of Cancer
,15
(5)
Background: Overexpression of aspartate β-hydroxylase (ASPH) in human tumors contributes to their progression by stimulating cell proliferation, migration, and invasion. Several signaling pathways affected by ASPH have ...
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Impacts of COVID-19 pandemic through decomposition of life expectancy according to leading causes and place of death in Czechia
original article
embargoed access
published version
2023
,Scientific Reports
,Neuveden
(13)
While the direct effects of the pandemic are well documented, less is known about the indirect ones, including changes in healthcare provision or human behavior. This paper aims to study the impact of indirect consequences ...
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Introduction of new MS instrument
lecture
open access
published version
2023
Introduction of methods available in our service laboratory with an emphasis on advanced proteomics methods - Protein cellular localization and thermal stability of proteins. Description of targeted proteomics and possibilities ...
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ABCB1 Amplicon Contains Cyclic AMP Response Element-Driven TRIP6 Gene in Taxane-Resistant MCF-7 Breast Cancer Sublines
original article
open access
published version
2023
,Genes
,14
(2)
A limited number of studies are devoted to regulating TRIP6 expression in cancer. Hence, we aimed to unveil the regulation of TRIP6 expression in MCF-7 breast cancer cells (with high TRIP6 expression) and taxane-resistant ...
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Genome sequence of parvovirus from budgerigar (Melopsittacus undulatus)
original article
open access
published version
2023
,Microbiology Resource Announcements
,12
(11)
Here, we report a parvovirus genome identified in Melopsittacus undulatus.The genome is 4,547 bp long and codes for two major open reading frames (ORFs): the non-structural replicase protein 1 (NS1) and the structural ...
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Co oko nevidí na Jüttnerově glóbu z roku 1839
What the eye does not see on Jüttner's globe from 1839
poster
open access
published version
2023
Příspěvek se zabýval popisem, digitalizací a zpřístupněním starého glóbu od Josefa Jüttnera z roku 1839, který pochází z depozitáře jedné z nejvýznamnějších středoevropských sbírek. Cílem autorů bylo připravit postup pro ...
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Analýza vodstva na Aretinově mapě Čech
Water analysis on Aretin's map of Bohemia
lecture
open access
published version
2023
Aretinova mapa Čech s názvem Regni Bohemiae nova et exacta descriptio z roku 1619 patří mezi naše nejstarší kartografická díla. Příspěvek představil výsledky komplexních obsahových a kartometrických analýz vodstva, který ...
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Role of E2/E3 ubiquitin ligase, UBE2O, in Hepatitis B virus replication
abstract in conference proceedings
open access
published version
2023
,Czech Chemical Society Symposium Series
,21
(5)
Chronic hepatitis represents a life-long liver disease caused by infection of Hepatitis B virus (HBV) and affecting more than 250 million people worldwide. Since HBV replication is completely dependent upon host cell protein ...
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Bioinformatics analysis of immune characteristics in tumors with alternative carcinogenesis pathways induced by human papillomaviruses
original article
open access
published version
2023
,Virology Journal
,20
(1)
Human papillomaviruses (HPVs) induce a subset of head and neck squamous cell carcinomas (HNSCC) and anogenital cancers, particularly cervical cancer (CC). The major viral proteins that contribute to tumorigenesis are the ...
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Discovery of Small Molecule Activators of NRF1 Transcriptional Activity Preventing Protein Aggregation
abstract in conference proceedings
open access
accepted version
2023
The intracellular accumulation of abnormal proteins exceeding their degradation can cause imbalance in proteostasis resulting in proteotoxic stress that leads to severe pathological stages. This state relates to proteasome ...
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Does advanced maternal age explain the longer hospitalisation of mothers after childbirth?
original article
open access
published version
2023
,PLoS One
,18
(4)
BACKGROUND: Fertility postponement, which has comprised the most significant reproductive trend in developed countries over the last few decades, involves a number of social, personal and health consequences. The length ...
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Does Advanced Maternal Age Comprise an Independent Risk Factor for Caesarean Section? A Population-Wide Study
original article
open access
published version
2023
,International Journal of Environmental Research and Public Health
,20
(1)
The paper aims to investigate the association between the mother's age and the risk of caesarean section when controlling for health factors and selected socio-demographic characteristics. The analysis employs anonymized ...
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Combining Polymerization and Templating toward Hyper-Cross-Linked Poly(propargyl aldehyde)s and Poly(propargyl alcohol)s for Reversible H2O and CO2 Capture and Construction of Porous Chiral Networks
original article
open access
published version
2023
,Polymers
,15
(3)
Two series of hyper-cross-linked microporous polyacetylene networks containing either -[CH=C(CH=O)]- or -[CH=C(CH2OH)]- monomeric units are reported. Networks are prepared by chain-growth copolymerization of acetal-protected ...
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Catching a New Zeolite as a Transition Material during Deconstruction
original article
open access
published version
2023
,Journal of the American Chemical Society
,145
(16)
Zeolites are key materials in both basic research and industrial applications. However, their synthesis is neither diverse nor applicable to labile frameworks because classical procedures require harsh hydrothermal conditions, ...
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The detection of hypoxia markers in non-HPV and HPV-associated head and neck cancers: implications to patient survival
abstract in conference proceedings
open access
published version
2023
,Czech Chemical Society Symposium Series
,21
(5)
In the microenvironment of growing solid tumors, oxygen level often decreases and a hypoxic state is induced. This can lead to a worse treatment response and poor patient prognosis. One of the hypoxia-responsive genes ...
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Can the type of oncogenic transformation by human papillomaviruses influence the choice of cancer immunotherapy?
abstract in conference proceedings
open access
published version
2023
,Czech Chemical Society Symposium Series
,21
(5)
High-risk human papillomaviruses can induce malignant transformation of cells resulting in anogenital cancers, particularly cervical cancer (CC), and a proportion of head and neck squamous cell carcinomas ...
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Mouse PML protein isoforms and their role in Mouse Polyomavirus infection
abstract in conference proceedings
open access
published version
2023
,Czech Chemical Society Symposium Series
,21
(5)
Promyelocytic leukaemia nuclear bodies (PML NBs) are dynamic, spherical, membrane-lessstructures composed of the main scaffold PML protein and a variety of stable or transient partner proteins. Apart from ...
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Sand Flies and Toscana Virus
abstract in conference proceedings
open access
accepted version
2023
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,21
(5)
Phlebovirus toscanaense (Toscana virus, TOSV) from the Phenuiviridae family is an emerging but still neglected human pathogen. Infections vary from non-symptomatic forms through febrile illness to CNS disease, rarely death. ...
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Understanding the interplay between MPyV infection and nuclear lamina
abstract in conference proceedings
open access
published version
2023
,Czech Chemical Society Symposium Series
,21
(5)
The nuclear lamina (NL) is a dense meshwork of intermediate filaments V, type A lamins (lamin A/C), type B lamins and membrane associated proteins. It is located below the inner nuclear membrane. NL maintains the shape and ...
